Measurement of plasma PIVKA-II, immunoreactive prothrombin and BaSO4 non-absorbable prothrombin before and after vitamin K administration in hepatoma patients.

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Vitamin K and the Biosynthesis of Prothrombin

Highly purified dicoumarol-induced bovine prothrombin, which does not bind calcium ions and has no prothrombin activity, has been structurally compared with normal prothrombin. Quantitative amino acid and carbohydrate analysis gave identical results for both prothrombins, as did analysis of the NHz-terminal and the COOH-terminal amino acids and molecular weight determination with the sodium dod...

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ژورنال

عنوان ژورنال: Kanzo

سال: 1991

ISSN: 0451-4203,1881-3593

DOI: 10.2957/kanzo.32.670